The half-life of caffeine in the body can range from 2 1/2 hours to 12 hours. Because of genetic differences, some of us metabolize caffeine much more quickly than others.
Typical half-life is probably about five hours, which means caffeine typically stays in the body for about 10 hours.
So as a rule of thumb, if you want to go to sleep by midnight — and stay asleep — it’s probably best not to drink coffee after 2 p.m
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